A recent review based on data collected from MEDLINE, PubMed, Embase showed that absorbable inferior vena cava (IVC) filters are potentially more effective and safer than the standard IVC filters, theoretically. The review, published by Joanna K.L. Wong, noted that the absorbable IVC filters reabsorb themselves over time, making it unnecessary to retrieve them and preventing the risks of filter removal.
The review aimed to evaluate the current design of absorbable IVCs from the developmental stage to completion. It assessed the effectiveness of IVCF, the possible complications, and the limitations and areas for future research.
Wong searched the databases of MEDLINE, PubMed, and Embase electronically, and relevant studies manually. Two independent reviewers carried out the study selection and data extraction using predetermined criteria and a pre-made performa for storage.
The reviewers performed a risk of bias test (RoB) for both in vitro and in vivo studies, respectively, using established RoB tools. The researchers conducted several studies, but only eight were suitable for Wong’s publication. Five were from in vivo, while three were from in vitro studies.
There was no evidence of a clinical trial, and the result showed that the risk of bias varied moderately to high for in vivo and in vitro studies. Wong stated that overall, they found evidence from both studies that absorbable IVC filters were effective in clot capturing, self-reabsorption and could reduce the complications associated with the standard IVC filters.
However, Wong pointed out that there remains an extensive lack of statistical analysis and control groups to determine the significance of the result. Additionally, she noted that the features are promising, but there’s a need for further research to determine the absorbable filter’s ideal characteristics and proceed to human trials.
If you or a loved one were injured by a defective IVC Filter, contact a mass tort attorney. Your lawyer will review your case and let you know if your case qualifies for a mass tort claim.