New Risks of Elderly Patients Taking Proton Pump Inhibitors?


While the oncology Community has long been concerned with proton pump inhibitors and their apparent link to both stomach and esophageal cancer, osteo studies show new concerns. Doctors and medical teams for the elderly and specifically those treating rheumatoid arthritis and other Osteo diseases have found consistent osteoporotic fracture risks associated with patients taking proton-pump inhibitors.

Initially, this discussion came up at the American Society for Bone and Mineral Research meeting in 2020. The meeting took place virtually from September 11th to September 15th, with the Rheumatology Advisor reporting on what the leading experts in Rheumatology had to say about proton pump inhibitors.

Proton pump inhibitors took the spotlight, but researchers and doctors acknowledge that it relied on the accompaniment of oral glucocorticoids. What study was done through clinical practice research data link between the years of 1997 and 2017. Medical records show from this time span that general practitioner clinics within the UK clearly show the possibility of fractures when patients were taking oral glucocorticoids and proton pump inhibitors. The primary finding was that an osteoporotic fracture such as a fracture of the hip, humerus, forearm, pelvis, ribs, and vertebrae were substantially higher for elderly patients taking both medications.

In the research data of 12,351 patients, there were 1,411 osteoporotic fractures. The concern from the medical community is that these proton pump inhibitors already come with a variety of high-risk issues, including the development of cancer. Cancer risks are typically higher among the elderly, and when you add in cancer risk with the risk of osteoporosis fracture you’re looking at deteriorating a person’s quality of life.

Researchers from this study and at the annual meeting the American Society for Bone and Mineral Research, acknowledged that high life expectancies and high consumption of PPIs will probably result in serious concern over the upcoming years. Contact our experienced mass tort attorneys right away.


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